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Eur Rev Med Pharmacol Sci ; 24(10): 5783-5787, 2020 May.
Article in English | MEDLINE | ID: covidwho-542679

ABSTRACT

In December 2019, Coronavirus disease 2019 (COVID-19) emerged in Wuhan and rapidly spread throughout China and the rest of the world. COVID-19 is currently a global pandemic. There are cytokine storms in severe COVID-19 patients. Interleukin-6 plays an important role in cytokine storm. Tocilizumab is a blocker of interleukin-6 receptor, which is likely to become an effective drug for patients with severe COVID-19. Here, we reported a case in which tocilizumab was effective for a critical COVID-19 patient.


Subject(s)
Antibodies, Monoclonal, Humanized/therapeutic use , Coronavirus Infections/drug therapy , Pneumonia, Viral/drug therapy , Betacoronavirus/isolation & purification , C-Reactive Protein/analysis , COVID-19 , Coronavirus Infections/pathology , Coronavirus Infections/virology , Humans , Leukocyte Count , Lymphocyte Count , Male , Middle Aged , Pandemics , Pneumonia, Viral/pathology , Pneumonia, Viral/virology , Receptors, Interleukin-6/immunology , SARS-CoV-2 , Tomography, X-Ray Computed
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